Impact of Prehabilitation in Oncology Via Exercise - Breast Cancer
Our primary aim is to assess safety, feasibility, and acceptability of prehabilitative (pre-treatment) exercise in breast cancer patients. These will be defined as follows:
Safety: Data from the primary investigators? prior trials indicate that we could expect up to 25% of the participants to experience a musculoskeletal impairment that would be mild (e.g., not require treatment alterations). We also expect an injury rate of 5% for musculoskeletal injuries (defined as symptoms lasting a week or longer and or requiring the attention of a medical professional). Feasibility: We will consider the intervention feasible if 50% of included patients actually do at least half of the exercise sessions prescribed for 2 weeks or more. Acceptability: We will consider the intervention to be acceptable if more than 50% of the patients approached agree to receive at least the first exercise session.
1.3 Secondary Study Endpoints Breast cancer-related symptoms (via revised version of the ESAS-r and EORTC QLQ-BR23), Quality of life (via EORTC QLQ-C30), fatigue (via MFI-20), mood, sleep (via PSQI), physical function (various assessments), treatment-related complications (via the medical record or questionnaires; e.g. onset of lymphedema, pain, impaired shoulder mobility), physical activity behavior (SQUASH) and uptake of post-treatment rehabilitation measures post primary cancer treatment