Clinical Studies Search

Protocol Summary


Protocol No.
PSCI-18-127
Prinicipal Investigator
Neves, Rogerio
Phase
Phase III
Age Group
Adult
Scope
National
Secondary Protocol No.
EA6174
Title
A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma
Objective
Primary Objective:
To compare Overall Survival (OS) and Recurrence Free Survival
(RFS) as co-primary endpoints across the two arms.

Secondary Objective:
To evaluate adverse events.
To evaluate Distant Metastasis Free Survival (DMFS).
To evaluate the impact of radiation on clinical outcomes (OS, RFS,
DMFS).
Applicable Disease Sites
Other Skin
Status
Open
Participating Institutions
Hershey Medical Center