Clinical Studies Search

Protocol Summary


Protocol No.
PSCI-21-160
Prinicipal Investigator
Zheng, Hong
Phase
Phase I/II
Age Group
Adult
Scope
National
Secondary Protocol No.
ASTX727-07
Title
A Single-Arm, Open-Label Pharmacokinetic, Safety, and Efficacy Study of ASTX727 in Combination with Venetoclax in Adult Patients with Acute Myeloid Leukemia
Objective
To evaluate the potential of drug-drug interaction: effect of ASTX727 on PK of venetoclax. To evaluate the potential of drug-drug interactions: effect of venetoclax on PK of ASTX727. To evaluate the safety of ASTX727 and venetoclax combination therapy.
Applicable Disease Sites
Leukemia, other
Status
Open
Participating Institutions
Hershey Medical Center