A Single-Arm, Open-Label Pharmacokinetic, Safety, and Efficacy Study of ASTX727 in Combination with Venetoclax in Adult Patients with Acute Myeloid Leukemia
Objective
To evaluate the potential of drug-drug interaction: effect of ASTX727 on PK of venetoclax. To evaluate the potential of drug-drug interactions: effect of venetoclax on PK of ASTX727. To evaluate the safety of ASTX727 and venetoclax combination therapy.