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Protocol Summary


Protocol No.
PSHCI-13-077
Prinicipal Investigator
Zheng, Hong
Phase
NA
Age Group
Adult
Scope
Local
Title
T-Cell Exhaustion in Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myelogenous Leukemia
Objective
Our long-term goal is to develop rational new immunotherapeutic for relapsed leukemia post alloSCT by inhibiting T cell exhaustion pathway. The specific objective of this proposal is 1) to characterize the development of T cell exhaustion in patients underwent alloSCT for AML; 2) to determine the prognostic value of T cell exhaustion in patients with leukemia relapse post alloSCT.
(Utilizing banked specimens from 2000-186)
Applicable Disease Sites
Myeloid and Monocytic Leukemia
Status
Open
Participating Institutions
Hershey Medical Center
Contact
Name
Hong Zheng
Phone No.
+1 717-531-0003
E-mail
hzheng@pennstatehealth.psu.edu